VALUABLE INSIGHTS & ADVICE FROM OUR SENIOR ONCOLOGIST
Dr. Vikas Goswami
Dr. Vikas Goswami is a highly experienced Medical Oncology Senior Consultant and Myeloma Cancer Specialist at Max Healthcare (Vaishali, Patparganj, Greater Noida, and Noida). Before joining Max Hospital, he was associated with the Fortis Group of Hospitals & IOSPL.
He is a well-trained medical oncologist, having great recognition and reputation at a national and international level. He has received much appreciation for his ethical and professional clinical approach.
- MBBS: Maulana Azad Medical College, New Delhi
- M.D. (Internal Medicine): Gandhi Medical College, Bhopal
- ECMO: European Society of Medical Oncology
- D.N.B. (Medical Oncology): Rajiv Gandhi Cancer Hospital & Research Institute
About Multiple Myeloma
Multiple myeloma cancer is a disease of plasma cells. Normal plasma cells are seen in the bone marrow and are a necessary part of the immune system. The immune system carries many different compartments to work collectively to fight infections and other diseases. Lymphocytes (lymph cells) are among the main kinds of white blood cells in the immune system and involve T cells and B cells.
There are, however, other plasma cell diseases that also have abnormal plasma cells but do not match the criteria to be called active multiple myeloma. These other plasma cell disorders include:
- Light chain amyloidosis.
- Monoclonal gammopathy of uncertain significance (MGUS)
- Solitary plasmacytoma
- Smoldering multiple myeloma (SMM)
SIGN & SYMPTOMS
Symptoms of Multiple Myeloma
Signs and symptoms of multiple myeloma can change and, beginning in the disease; there may be none. When signs and symptoms do happen, they can include the most common types of signs and symptoms such as:
- Weight loss
- Weakness or numbness in your legs
- Swelling in your legs
- Mental fogginess or confusion
- Pain, especially in your spine or chest
- Extreme thirst
- Frequent urination
- Loss of appetite
CANCER IS DIAGNOSED
How Myeloma Cancer is Diagnosed?
Blood or Urine Tests
- Blood tests.Lab opinion of your blood may explain the M proteins generated by myeloma cells. Another abnormal protein generated by myeloma cells — called beta-2-microglobulin — may be detected in your blood and give your doctor evidence about the aggressiveness of your myeloma.
- Urine tests.A review of your urine may show M proteins referred to as Bence Jones proteins when they’re recognized in the urine.
- Imaging tests may be suggested to identify bone problems linked with multiple myeloma. Tests may include an:X-ray.An x-ray is a test to formulate a picture of the structures inside of your body, using a small number of radiation.MRI.An MRI uses magnetic fields create complete images of the body. It can show if the normal bone marrow has been restored by myeloma cells.CT.A CT scan formulates a detailed, cross-sectional picture that shows any irregularities or tumors in soft tissues.PET.A PET scan is generally combined with a CT scan named a PET-CT scan. A PET scan is a method to build pictures of organs and tissues inside the body.
Bone Marrow and Biopsy
- In a bone marrow biopsy, a doctor will extract a little piece of bone that includes marrow. For a bone marrow purpose, a doctor will remove a small amount of liquid bone marrow containing marrow cells.These two methods are related and generally done at the same time to check the bone marrow. A bone marrow biopsy presents:
- information about the volume of disease
- its aggressiveness
- molecular/genetic irregularities that help predict the disease course
Treatments Recommended for Myeloma Cancer Patients
Myeloma cancer disease is treated in many ways. It depends on the sort of myeloma cancer disease and how this disease has spread among peoples. People with myeloma cancer often take more than one kind of treatment.
Targeted therapy is typically used to treat multiple myeloma. It uses drugs to target particular molecules (such as proteins) on or inside cancer cells. These molecules help signs that tell cells to grow or divide. Another name of targeted therapy is termed molecular targeted therapy. Targeted therapy consist:
- destroy multiple myeloma cells
- decrease the number of cancer cells in the body before a stem cell transplant
- kill cells in the bone marrow as part of stem cell transplant conditioning
- create a stem cell transplant work better
Immunotherapy is a range of treatments that support a person’s immune system to destroy cancer cells. Immunotherapy is a likely new treatment option for multiple myeloma patients, with the potential to succeed in long term cancer relief similar to the results of allogeneic bone marrow transplantation of blood stem cells.
Radiation therapy practices high-energy beams or particles to destroy cancer cells. Radiation may be practiced to treat damaged bone sections by myeloma that have not responded to chemotherapy and other drugs and are making pain or near breaking. It’s also the most popular treatment for solitary plasmacytomas. Symptoms involve an immediate change in sensation, leg muscle’s primary weakness. Radiation therapy’s main aim is removing cancer with the help of machines from outside the body.
Chemotherapy is treatment with cancer-fighting drugs. Because these medicines pass into your bloodstream and enter all parts of your body, they’re an outstanding choice to kill myeloma cells. It targets cells that develop and divide quickly, as cancer cells do. It can also influence some fast-growing healthy cells, like those of the skin, hair, intestines, and bone marrow. That’s what creates some of the side effects of the treatment. It depends on the type of cancer you have and how far along it is.
Health Issues from Multiple Myeloma
Low Blood Count
In multiple myeloma, plasma cells’ extra growth in the bone marrow can push out normal blood-forming cells, pointing to low blood counts.
- Multiple myeloma can also produce the level of platelets in the blood to become low (called thrombocytopenia).
- This can cause anemia (lack of red blood cells). People with anemia become weak and exhausted.
Bone & Calcium Problems
Myeloma cells also prevent cells that help maintain bones healthy. two kinds of bone cells work together to keep bones healthy and strong:
- Osteoclastsbreak down old bone
- Osteoblastslay down new bone
Myeloma cells produce a substance that indicates the osteoclasts to speed up destroying the bone.
Unusual plasma cells cannot protect the body from infections. Natural plasma cells produce antibodies that attack germs. In multiple myeloma, the myeloma cells push out the normal plasma cells so that antibodies to fight can’t cause the infection. The antibody produced by the myeloma cells does not assist in fighting infections.
Myeloma cells produce an antibody that can hurt the kidneys, leading to kidney damage and kidney failure.
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TREATMENTS IN DELHI & NOIDA
Myeloma Cancer Treatment in Delhi & Noida
Zeeva Clinic offers personalized treatment to patients from across the country using the world’s most advanced myeloma cancer screening and treatment technology. We are here to save the lives of people, but we also have the opportunity to offer tailored care to elderly patients who may have other health problems besides myeloma cancer.
Our multidisciplinary team of myeloma cancer treatment in Delhi and Noida provides Support and care that will be involved to coordinate treatment throughout the journey efficiently. We have access to the most advanced myeloma cancer screening and treatment technologies in the world, and we have the highest quality of care for our patients and their families.
We understand your challenges and concerns and can give you encouragement and helpful advice. We contact survivors who have completed treatment so that we can get them at any time during and after their cancer treatment. You will support us throughout your journey through myeloma cancer screening, and we understand and support you.
Dr Vikas Goswami, director of Zeeva Clinic and myeloma cancer specialist in Delhi and Noida, believes that myeloma cancer is curable if diagnosed and treated correctly at the right time. We are continually striving to equip our patients with excellent treatment to diagnose and treat it most effectively. We do our best to understand the various diseases and their causes and to offer patients the best medicines, with a specialized medical team.
Frequently Asked Questions
01/ How do you get Myeloma Cancer?
It’s not apparent what causes myeloma. Doctors recognize that myeloma starts with one abnormal plasma cell in your bone marrow — the kind, blood-producing tissue that pervades in the center of most of your bones. The abnormal cell multiplies quickly.
02/ Where does multiple myeloma spread to?
Myeloma Cancer cells can also grow into (invade) nearby areas. And they canspreadto different parts of the body. This is called metastasis. Multiplemyeloma is cancer that starts in plasma cells in your bone marrow.
03/ What is the best treatment for multiple myeloma?
Treatments for myeloma
- Targeted therapy. Targeted medicine treatments concentrate on specific weaknesses present in cancer cells. …
- Immunotherapy. It practices your immune system to fight cancer.
- Chemotherapy. It practices medicines to kill cancer cells. …
- Bone marrow transplant.
- Radiation therapy.
04/ What are the common symptoms of Multiple Myeloma?
- Increased thirst.
- Common infections.
- Weight loss.
- Muscle weakness.
05/ What is the treatment for Stage 1 multiple myeloma?
If the areas of infected bone continue to cause symptoms, radiation therapy may be used. Patients with multiplemyeloma also get supportive treatments, such as transmissions to tackle low blood cell counts and antibiotics, and sometimes intravenous immunoglobulin (IVIG) for infections.
06/ How bad is myeloma cancer?
Myeloma formulates unusual plasma cells, dropping less room for the typical white and red blood cells to prevent the body from being healthy. When the myeloma cells divide and grow, they can cause damage to the bones and attack the blood, kidneys, and immune system.