Semen Sample Collection and Preparation
A sample of semen (fresh or frozen) is collected and prepared by the embryologist. For preparation, all the impurities are removed from the sample by treating it with a specific solution.
For injection, the embryologist will now select a sperm by examining them under a microscope. The microscope will allow the embryologist to look at the sperm through a magnification of more than 6000X. This ensures that the sperm selected is of the best quality and health.
Just like ICSI, the eggs are collected from the female partner and washed to remove the unwanted particles. The eggs are then examined under a microscope and healthy ones are selected for fertilization with the sperm.
The selected sperm(s) is then put in a fine glass needle and then injected into the chosen egg(s) for fertilization. This fertilized egg(s) is cultured in a sterile culture petri dish in an incubator.
Once the embryo(s) have been cultured and are ready to be transferred, the female partner will be called to the clinic and will have the embryo(s) inserted into her uterus. After approximately 14 days (2 weeks), a pregnancy test will be done to check if pregnancy has been achieved or not.
Intracytoplasmic Morphologically Selected Sperm Injection is an acronym for IMSI IVF. In IVF treatments, IMSI involves the insertion of sperm into the egg to enhance the fertilization process. High-power magnification allows the experts to see the sperm in detail, allowing them to find the sperm with the highest chance of being fertile for implantation into the eggs to give birth to a healthy baby.
In IMSI’s laboratory, experts use magnifying microscopes to evaluate normal sperms and distinguish between those with abnormalities from those without. Consequently, preventing the injection of abnormal sperms into the egg may reduce the chances of fertilization, reducing the success rate of IMSI treatment.
According to reports, the success rate of IMSI is 66%, while the success rate of normal sperm injection is 33%. In addition to IMSI’s advantages, there are some disadvantages as well:
- This technique doubles the pregnancy rate lowering the abortion rate by 60%.
- In this case, normal sperm is selected, reducing the chances of miscarriage.
- It helps to determine fertility hence enhancing fertility and pregnancy rates.
IMSI has a lot of disadvantages, which include:
- It is a time taking and expensive process.
- This leads to multiple pregnancies when compared to ICSI.
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FREQUENTLY ASKED QUESTIONS
01/ What Are The Success Rates Of IMSI?
The study shows that IMSI technology increased the success rate from 33% to 66%
02/ What are the success rate of PICSI fertility?
Physiological ICSI method is successful and has a higher success rate of 60%. In some cases, it may also increase from 80% to 90%.
03/ When IMSI is Recommended?
IMSI is recommended under the following circumstances:
- The male partner’s sperm counts are less
- The semen sample contains a higher level of abnormally shaped cells
- The previous outcomes have been negative
04/ What To Better ART Treatment ICSI Or IMSI?
The sperm micromanipulation like ICSI is very useful for treating couples in which the male partner has a less or no sperm concentration or motility or both. Also, the study has shown that IMSI, using spermatozoa selected under high magnification mainly associated with more pregnancy rates in couples with repeated implantation failures.
05/ What Are The Advantages Of IMSI?
Since it is possible to extract the healthiest, most motile and the potent sperm cells it gives the advantages in increasing the success rates of the fertilization process.
06/ How does IMSI IVF exclude abnormal sperms?
During IMSI (intracytoplasmic morphologically selected sperm injection) a sperm is tested by using a high-powered digital microscope. This microscope can enlarge the sperm image up to 6000-8000 times thereby allowing the fertility specialists to examine the sperm meticulously for any shape and size abnormalities and choose the best sperm for the fertilization process in ICSI IVF.