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Egg donation is a procedure wherein a fertile woman donates an egg, or oocyte, to some other woman to help her conceive. It is one of the parts of assisted reproductive technology or ART. The egg donation process commonly includes a doctor taking out an egg or eggs from the donor, fertilizing them in a laboratory, after which placing the ensuing embryos into the recipient’s uterus. Doctors do that by utilizing an implantation technique, for example in vitro fertilization (IVF).
Why Use an Egg Donor?
Egg donation is used for a woman who desires to have a baby but can’t get pregnant with her very own eggs. This can be due to the fact she was born without ovaries, is in menopause, did now no longer respond adequately to hormonal stimulation of her ovaries in the past, or has had bad egg or embryo quality with preceding donor egg IVF attempts.
Women can also select to apply for a donor if they have a genetic disorder that they do not want to pass directly to their children. The most common purpose why single women and couples turn to egg donation is bad egg quality because of advanced maternal age.
Who Uses Egg Donations?
1. Age-associated infertility (most usually for women age forty or older):
According to the Centers for Disease Control and Prevention (CDC), 30% of women between the ages of forty and forty-four experience infertility. Your probabilities of conceiving in any given month additionally turn out to be lower as you get older.
2. Low ovarian reserves (indicated through very excessive FSH levels or a low antral follicle count):
Having bad ovarian reserves means the probability of IVF treatment success is low. Poor ovarian reserves increase the chances of donor egg IVF cancellation.
3. A single male with a gestational carrier:
Men who’re single, yet desire to pursue parenthood can select a surrogate with an egg donor and become a father. This permits them to still have a biological connection to their children while not having a companion. Single men also can select embryo donation as an alternative for parenthood.
4. Gay male couple having a baby with a gestational carrier:
In gestational surrogacy, an embryo is constituted of a donor egg and one male companion’s sperm is implanted in a surrogate through in vitro fertilization. Because the egg comes from a donor, the surrogate isn’t always biologically associated with the child.
Egg Donation Requirements
An egg donor in the egg donation process goes through psychological and medical screening, which incorporates an intensive medical history, physical exam, and ovarian reserve evaluation to decide if she is probably the right donor candidate.
- Be between 23-35 years of age (as much as 31 for experienced donors)
- Have a Body Mass Index (BMI) lower than 29 Have no more than one incidence of identical cancer in family records (besides non-genetic cancers, which include leukaemia and lung)
- Have a family history without a critical heart disorder or heart attacks below age 55
- Not having psychiatric hospitalizations Be comfortable with giving yourself every day injections with small needles, like those used for insulin
- The egg donor receives hormone injections to result in the ovulation of a couple of eggs. Women evidently release one egg a month and the injections permit a massive quantity of eggs to mature at the same time. Once her eggs are mature and prepared for retrieval, her fertility doctor schedules the egg donation process.
- The egg donor is placed under sedation and her doctor makes use of an ultrasound-guided needle inserted into every mature follicle to retrieve every egg. The lab will try and fertilize numerous eggs in the laboratory utilizing the recipient’s partner’s sperm or selected donor sperm. This egg donation process is IVF i.e. – In Vitro Fertilization.
- A fertilized egg/embryo is transferred into the recipient’s uterus, then.
- In a clean transfer cycle, the donor and the recipient’s cycles are synchronized by utilizing medication.
- In a frozen transfer, the embryos are frozen and commonly transferred at a later time.
- Frozen transfers are occasionally applied in the order that preimplantation genetic screening for aneuploidy (an odd quantity of chromosomes) can be performed.
- If successful, the embryo will implant into the uterine lining and turn into a wholesome baby.
Egg Donor Cost And Sources
Commercial egg donor companies recruit, screen, and fit healthy donors with couples and individuals. Many infertility clinics additionally provide donated eggs from couples who’ve produced extra eggs.
In a few cases, the recipient may also ask a near friend or relative to donate her eggs. Recipients may also pick out a fresh cycle or a frozen egg donation cycle (from a frozen egg bank). In most cases, the egg donor cost varies depending upon certain conditions associated with the procedure. Many financial aspects need to be considered while going through the egg donation process.
Though the utilization of frozen donor eggs has become more common, there’s a reason fresh donor egg cycles are still the rule: the success rates continue to be higher. The results of a 2017 research reviewed the most recently available records and observed that a fertility cycle was 19% much more likely to result in a live birth if the egg used had never been frozen.
Egg Donation Success Factors
Success relies upon many elements such as the age of the egg donor, retrieval procedure, quality of sperm, and the recipient’s general fitness. As with all third-party reproduction processes, recipients must search for counselling to explore emotional issues and a skilled lawyer to guard there, and their potential children’s, rights.
1. How long does the egg donation procedure take?
In total, the egg donation procedure spreads over about three to five weeks of calendar time (more or less eight appointments).
2. Does the success rate vary by age?
In general, the uterus now no longer ages in the same way as the ovary. The success rate is the same for women in their third, fourth and 5th decade of life – assuming that the patient is in proper health and otherwise an appropriate candidate for this treatment.
3. Who gets donor eggs?
Couples commonly select this alternative because they are not able to conceive with the eggs of the partner who will convey the child. Women can not able to conceive with their very own eggs
4. Does the donor have any rights over their eggs?
According to contemporary laws, donors do not retain rights to eggs or ensuing embryos after donation.
5. How are donors screened?
Egg donors undergo an intensive screening procedure with the purpose to choose qualified candidates and help make sure that information furnished about the donor’s medical history and health status is accurate. The procedure consists of a medical evaluation (such as an exam of reproductive organs and blood tests to test hormone levels), genetic screening, STD and drug testing, and psychological counselling.
6. How exactly with the donor is the cycle of the recipient synchronized?
Birth control drugs and other hormones can be used to control the recipient’s periods and make sure she is prepared to obtain the donated eggs at the right time.